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First case of penicillin-resistant Streptococcus agalactiae (group B Streptococcus) isolated from an adult patient in Italy, February 2026

Year: 2026

Type: article

Abstract: A penicillin-resistant group B streptococcal (GBS) strain was identified in Italy, after isolation from the blood culture of a patient in their 80s with comorbidities. The isolate was multidrug-resistant and demonstrated by genome sequencing to be of serotype Ia, sequence type 23, and to possess the alp1 gene. Known and new point mutations were detected in the penicillin-binding-protein genes 2a and 2x. Although sporadic, penicillin-resistance in GBS is a serious concern for prophylaxis and therapy, so continued GBS surveillance remains important.

Source: Eurosurveillance

DOI: 10.2807/1560-7917.es.2026.31.20.2600374

Authors: Roberta Creti, Giovanni Gherardi, Monica Imperi, Andrea Zappavigna, Gabriella Tocci, Nicolò Rossi, Filippo Trapani, Giovanna Alfarone, Ilaria Marani, Anna Teresa Palamara, Giuliana Lo Cascio

Institutions: Istituto Superiore di Sanità, Azienda Unità Sanitaria Locale Piacenza, University of Parma

Language: English

Topic: Neonatal and Maternal Infections

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7162131586

FWCI:

Cites: 21

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