Use of Human Dose Prediction Metrics to Enable Discovery of AZD3470, an MTA-Cooperative PRMT5 Inhibitor in Clinical Evaluation
Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
Authors: James M. Smith, Bernard Barlaam, David Beattie, Lauren Bradshaw, Ho Man Chan, Sophie L. Cooke, Anna Cronin, Iain Cumming, Emma Dean, Judit É. Debreczeni, Iván del Barco Barrantes, Douglas Ferguson, Davide Gianni, Michael Grondine, James T. Lynch, Lisa McWilliams, Shaun Moore, Piotr Raubo, Yang Qu, Graeme R. Robb, Lixiang Tan, Jelena Urosevic, Mercedes Vazquez-Chantada, Pingping Wang
Institution: Pharmaron (China)
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: closed
OpenAlex ID: W7162134593