Work

Determination of 69 Pesticide Residues in 42 Batches of Platycodonis Radix and Dietary Risk Assessment Using Combined QuEChERS with GC-MS/MS and UHPLC-MS/MS

Year: 2026

Type: article

Abstract: This study aimed to establish a rapid analytical method for the determination of 69 pesticide residues in Platycodonis Radix using GC-MS/MS and UHPLC-MS/MS, as well as carry out a dietary risk assessment on 42 batches of Platycodonis Radix samples collected from different geographical origins. Samples were prepared using the QuEChERS method, followed by high-speed centrifugation and membrane filtration, and the target pesticides were analyzed in selected reaction monitoring (SRM) mode via GC-MS/MS and in multiple reaction monitoring (MRM) mode via UHPLC-MS/MS. Among the 42 tested batches of Platycodonis Radix samples, 3 out of 27 pesticide compounds were detected via GC-MS/MS screening, while only 1 pesticide compound was positive from the 42 compounds determined via UHPLC-MS/MS, and the risk assessment results demonstrated that both chronic and acute dietary exposure risks of all detected pesticides were considerably lower than 1.

Source: Foods

DOI: 10.3390/foods15111835

Authors: Jing Ma, Xinyue Qiu, Suiqing Chen, Haibo Wang, Xiaoya Sun

Institutions: Henan University of Traditional Chinese Medicine, National Medical Products Administration

Language: English

Topic: Pesticide Residue Analysis and Safety

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: gold

Estimated APC paid: $3,499