Work

Comparison of 2% lidocaine with epinephrine and 4% articaine with epinephrine in local anesthesia of maxillary molars affected by molar incisor hypomineralization: a randomized controlled trial

Year: 2026

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: The use of local anesthesia is essential for pain control during the treatment of MIH-affected molars. This study aimed to compare injection-related pain and anesthetic efficacy between 2% lidocaine with epinephrine (LE) and 4% articaine with epinephrine (AE) in the MIH-affected maxillary molars of pediatric patients. Twenty-six children aged 6 to 12 years requiring restorative treatment of MIH-affected maxillary molars were enrolled. Participants randomly received one of the two anesthetic solutions (LE or AE) at the first visit; the other solution was administered at the second visit. Injection-related pain and anesthetic efficacy were evaluated subjectively using the Wong-Baker Faces ® pain rating (WBF) scale and behaviorally using the Face, Legs, Activity, Cry, and Consolability (FLACC) scale. No statistically significant difference was found between LE and AE in injection-related pain on either scale ( P > 0.05). Similarly, no statistically significant difference was recorded between the two solutions in the anesthetic efficacy for MIH-affected maxillary molars, according to both scales ( P > 0.05). These findings indicate that both LE and AE provide comparable clinical outcomes, supporting the use of either solution as a local anesthetic for MIH-affected maxillary molars in pediatric patients.

Source: Scientific Reports

DOI: 10.1038/s41598-026-54698-4

Authors: Mai Haidar, Nabih Raslan

Institution: Latakia University

Language: English

Topic: Dental Anxiety and Anesthesia Techniques

Subfield: Oral Surgery

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,690