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Mitigating Excessive Mitochondrial Fission Through the Development of a Selective Macrocyclic Inhibitor Targeting Fis1/Mid51 Signaling

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Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.6c00333
Authors: Mulate Zerihun, Sayan Chakraborty, Ayetenew Abita, Suchismita Dey, Ivan Lopez, Rani Wainer Shlomo, Mahesh Kumar Cinthakunta Sridhar, Liron Davis, Offir Ertracht, Shaul Atar, Deborah E. Shalev, Marta De Zotti, Bereketeab Haileselassie, Nir Qvit
Institutions: Bar-Ilan University, Stanford Medicine, Stanford University, Western Galilee Hospital, Hebrew University of Jerusalem, Azrieli College of Engineering Jerusalem, University of Padua
Language: English

Topic: Mitochondrial Function and Pathology
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Israel Science Foundation, National Heart, Lung, and Blood Institute, Stanford Maternal and Child Health Research Institute
Awards: Role of Altered Mitochondrial dynamics in Graft Versus Host Disease, G924307579
OpenAlex ID: W7162199027
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Cites: 76
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