Work

Discovery of FYJ-195 as a Highly Potent FLT3 Inhibitor against Multiple Acquired Resistance Mutations in Acute Myeloid Leukemia

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c00648

Authors: Jin Yang, Ling-Yu Zhang, Xing-Feng Ni, Ming-Yu Bai, Xu Wang, An-Qi Fu, Min-Hui Chen, Meng-Yuan Zhang, Nuo Qiao, Zi-Xuan Wang, Qing-Qing Li, Shu Cai, Ying Wang, Yu-Sheng Yao, Yan-Cheng Yu, Wei-Dong Chen, Shan-Liang Sun, Zhang Zhang, Nian-Guang Li, Zhi-Hao Shi

Institutions: Nanjing University of Chinese Medicine, Jinan University, First Affiliated Hospital of Shantou University Medical College, China Pharmaceutical University

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Priority Academic Program Development of Jiangsu Higher Education Institutions, National Key Research and Development Program of China

Awards: G3270552589, G5913327515, G6771631603, G7530881489

OpenAlex ID: W7162209559

FWCI:

Cites: 39

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