Takotsubo Cardiomyopathy (Stress-Induced Cardiomyopathy): A Narrative Review
Year: 2026
Type: review
Abstract: Background:Takotsubo cardiomyopathy (TCM), also known as stress-induced cardiomyopathy or “broken heart syndrome,” is a transient left ventricular systolic dysfunction that clinically mimics acute coronary syndrome (ACS) but occurs in the absence of obstructive coronary artery disease. Objective:This narrative review summarizes current evidence regarding the pathophysiology, clinical presentation, diagnostic approach, and management of Takotsubo cardiomyopathy. Methods:A narrative review of literature published between January 2005 and March 2025 was conducted using PubMed, Google Scholar, and major cardiology society guidelines including the European Society of Cardiology and American Heart Association. Articles written in English focusing on epidemiology, pathophysiology, diagnosis, and management of Takotsubo cardiomyopathy were reviewed. Results:Takotsubo cardiomyopathy predominantly affects postmenopausal women and is typically triggered by emotional or physical stress. It presents with chest pain, electrocardiographic changes, and mild to moderate elevation of cardiac biomarkers. Left ventricular dysfunction is usually transient, with recovery within days to weeks. Although prognosis is generally favorable, serious complications such as heart failure, arrhythmias, and cardiogenic shock may occur. Conclusion:Takotsubo cardiomyopathy is an important differential diagnosis of acute coronary syndrome. Early recognition, appropriate imaging, and supportive management are essential to improve outcomes.
Author: Basan, Ganchimeg
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7162255183