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Phase II study of olaparib plus ATR inhibitor ceralasertib in patients with metastatic breast cancer and germline BRCA1/2 pathogenic variants who progressed on prior PARP inhibitor therapy.

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Year: 2026
Type: conference-abstract
Source: Journal of Clinical Oncology
DOI: 10.1200/jco.2026.44.16_suppl.1142
Authors: Banu Arun, Adaeze Nwosu Iheme, Nuhad K. Ibrahim, Rachel M. Layman, Ajit Kumar Bisen, David Luis Ramirez, Madison H. Williams, Giancarlo Moscol, Vicente Valero, Oluchi Oke, Azadeh Nasrazadani, Mariana Chavez Mac Gregor, Clinton Yam, Angelica M. Gutierrez, Cynthia Tamez, Katharina Schlacher, John A. Tainer, Simon Smith, Junjie Chen, Constance T. Albarracin
Institutions: The University of Texas MD Anderson Cancer Center, AstraZeneca (United Kingdom)
Language: English

Topic: PARP inhibition in cancer therapy
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: Cancer Prevention and Research Institute of Texas
OpenAlex ID: W7162559898
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