Discovery of the Orally Bioavailable Isoform Selective Janus Kinase 1 (JAK1) Compound Povorcitinib (INCB054707) for the Treatment of Inflammatory and Autoimmune Diseases
Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
Authors: Jincong Zhuo, Yun-Long Li, Ding-Quan Qian, David M. Burns, Song Mei, Maria Rafalski, Meizhong Xu, Ganfeng Cao, Yongchun Pan, Zhongjiang Jia, Ravi Jalluri, Leslie B. Epling, Gustavo Fenalti, Marc C. Deller, Jessica Procak, Maryanne Covington, Xin He, Robert Collins, Matthew Stubbs, Krista Burke, Julian Oliver, Alex Margulis, Jason Boer, Richard Wynn, Peggy Scherle, Sharon Diamond, Robert Newton, Yan Zhang, Brian Metcalf, Wenqing Yao
Institution: Incyte (United States)
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: closed
Funder: Incyte
OpenAlex ID: W7162570595