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Updated design of INVOKE: A phase 1 study of OKN4395, a first-in-class EP2/EP4/DP1 triple prostanoid receptor antagonist, in patients with advanced solid tumors.

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Year: 2026
Type: article
Study design: Study Protocol
Source: Journal of Clinical Oncology
DOI: 10.1200/jco.2026.44.16_suppl.tps2681
Authors: Stephane Champiat, Luke Kuttschreuter, Neal Shiv Chawla, Louise Carter, Steven Chuan-Hao Kao, Victoria K. Woodcock, Sarah Benafif, T.R. Jeffry Evans, Timothy Guy Humphries, Harriet S. Walter, Andy Karabajakian, Alexandre Grimaldi, Caroline Hoffmann, Andrew Pierce, Kamlesh Kumar Sankhala
Institutions: The University of Texas MD Anderson Cancer Center, Sarcoma Oncology Center, The Christie NHS Foundation Trust, Chris O’Brien Lifehouse, Churchill Hospital, University College Hospital, University College London, Beatson West of Scotland Cancer Centre, University of Glasgow, Linear Clinical Research, University Hospitals of Leicester NHS Trust
Language: English

Topic: Inflammatory mediators and NSAID effects
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W7162682574
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