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When both treatments unblinded, psychedelics not more effective than antidepressants

Year: 2026

Type: article

Abstract: A systematic review and meta‐analysis comprising 24 trials has concluded that when both psychedelic and antidepressant trials in the treatment of depression are unblinded, psychedelics are no more effective than open‐label antidepressants. The findings call into question some optimistic projections about the efficacy of psychedelics in depression treatment.

Source: The Brown University Psychopharmacology Update

DOI: 10.1002/pu.31464

Language: English

Topic: Psychedelics and Drug Studies

Subfield: Clinical Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W7162769194

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