Work

Copper Joins the Monoelectronic Game: Leveraging the Cu I Potential for SET‐, XAT‐, and HAT‐Driven Catalytic Organic Synthesis

Year: 2026

Type: article

Abstract: ABSTRACT The growing interest in sustainable organic synthesis using catalysts based on first‐row transition metals has highlighted their remarkable ability to participate in monoelectronic processes. These processes have become a complement to the traditional two‐electron chemistry associated with transition metals. Recognizing their novelty and transformative potential, we aim to analyze and emphasize the role of copper(I)‐based catalysts in building molecular complexity from simple feedstocks by leveraging strategies that involve electron, halogen, and hydrogen transfer processes (SET, XAT, and HAT, respectively). Here, we provide a practical overview of the field by examining the main reactivity trends and key factors for achieving efficient transformations, while also showcasing the current versatility and synthetic utility of these methodologies.

Source: ChemCatChem

DOI: 10.1002/cctc.70830

Authors: Antonio Torres‐Calis, Juventino J. García

Institution: Universidad Nacional Autónoma de México

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,500

Funder: Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México