Work

A multi-subunit autophagic capture complex facilitates degradation of ER-stalled MHC class I in pancreatic cancer

Year: 2026

Type: article

Source: Molecular Cell

DOI: 10.1016/j.molcel.2026.05.005

Authors: Marine Berquez, Alexander L. Li, Matthew A. Luy, Anthony C. Venida, Simon McDowall, Thomas O’Loughlin, Gilles Rademaker, Abhilash Barpanda, Jingjie Hu, Julian Yano, Arun P. Wiita, Luke A. Gilbert, Peter M. Bruno, Rushika M. Perera

Institutions: University of California, San Francisco, Icahn School of Medicine at Mount Sinai, Arc Research Institute, UCSF Helen Diller Family Comprehensive Cancer Center

Language: English

Topic: Autophagy in Disease and Therapy

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Arc Institute, Damon Runyon Cancer Research Foundation, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Targeting the autophagy-lysosome system to block pancreatic cancer, G2252769537, Role of Myoferlin in Preserving Lysosomal Membrane Integrity in Pancreatic Ductal Adenocarcinoma, G6113043618, Multiscale design and characterization of resilient lightweight perforated shellulars, Diabetes Research Center, Dissecting new mechanisms of lysosome quality control in health and disease, Identifying and disabling new pathways for macromolecular recycling in pancreatic cancer

OpenAlex ID: W7162811840

FWCI: 27.29

Cites: 70

Cited by: 10

Related to: 10