Anthropometric Obesity Indices were Stronger than CT-Based Indices in Associations with Carotid Intima-Media Thickness in Japanese Men
Year: 2019
Type: article
Study design: Observational Study
Abstract: AIM: Computed tomography (CT) can directly provide information on body compositions and distributions, compared to anthropometric indices. It has been shown that various obesity indices are associated with carotid intima-media thickness (IMT). However, whether CT-based obesity indices are stronger than anthropometric indices in association with atherosclerosis remains to be determined in a general population. METHODS: percentile of each index were compared. We also compared the slope of index with simultaneous adjustment for BMI in the same model. RESULTS: Areas of VAT and SAT were positively associated with IMT, but not stronger than those of anthropometric indices in point estimates. Among all obesity indices, BMI was strongest in association with IMT after adjusting for age and lifestyle factors or further adjusting for metabolic factors. In simultaneous adjustment models, BMI, but not CT-based indices, remained significant and showed the strongest association. CONCLUSIONS: In community-dwelling Japanese men, anthropometric obesity indices, BMI in particular, were more strongly associated with carotid atherosclerosis than CT-based obesity indices. The association of general obesity with carotid atherosclerosis was strong and adding CT-based obesity measure did not considerably influence in the association.
DOI: 10.5551/jat.47977
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
Awards: International comparison of subclinical atherosclerosis among the Japanese and American men aged 40-49, The impacts of ectopic fats in muscle, liver, and abdominal tissues on the metabolism related to glucose and insulin, Association between equol, a metabolite of soy protein, and atherosclerosis in a community-based general population, A study on determinants of subclinical atherosclerosis, Comparison Western Japan with Eastern Japan about the cause of asymptomatic cerebrovascular disorders and hippocampal atrophy in general Japanese men, Subclinical atherosclerosis and brain atrophy in general Japanese women : the second phase survey, Oral/gut microbiota and coronary calcification, A population-based epidemiological study on the association between mild cognitive impairment and atherosclerosis, Arrhythmia and subclinical cerebrovascular disease, International collaborative study on subclinical atherosclerosis and its risk factors in three populations in the US and Japan, A follow up study of fatty liver, lipoprotein particle sizes, and progression of subclinical atherosclerosis in middle aged men., Explorative Study on new biomarker of atherosclerosis, Subclinical atherosclerosis and brain atrophy in the general Japanese women, Epidemiological Study regarding to the development of fatty liver, metabolic abnormalities, and potential arteriosclerosis.
OpenAlex ID: W2946757433