Work

Modulation of Cell Barrier Dysfunction

Year: 2012

Type: article

Abstract: The invention provides prophylactic and therapeutic methods for administering a μ-opioid receptor antagonist, e.g., N-methylnaltrexone or a salt thereof, to treat cell barrier diseases and disorders, such as endothelial and epithelial cell barrier diseases and disorders, e.g., inflammatory bowel disease. Methods of reducing the symptoms of inflammatory bowel disease and the risk of developing inflammatory bowel disease are also provided.

Source: University of Chicago

DOI: 10.6082/penbc-2gp28

Authors: Alverdy, John C., Moss, Jonathan, Lingen, Mark W., Singleton, Patrick A., Garcia, Joe G. N.

Institution: University of Chicago

Language: English

Topic: Inflammatory Bowel Disease

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7163000122

FWCI:

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Related to: 10