Work

Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and T H 17 responses

Year: 2020

Type: article

Abstract: 17 cells occurring independently in both LN and lung. Thus, self-assembling peptide nanofiber vaccines may represent a novel, needle- and adjuvant-free means of eliciting protective immunity against fungal and bacterial infections at skin and mucosal barrier surfaces.

Source: Science Advances

DOI: 10.1126/sciadv.aba0995

Authors: Youhui Si, Qiaomu Tian, Fan Zhao, Sean H. Kelly, Lucas S. Shores, Daniel F. Camacho, Anne I. Sperling, Michael S. Andrade, Joel H. Collier, Anita S. Chong

Institutions: University of Chicago, Duke University

Language: English

Topic: Immunotherapy and Immune Responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,500

Funders: National Science Foundation, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, National Institute of Biomedical Imaging and Bioengineering

Awards: G1145435258, Medical Scientist National Research Service Award, IRF4+ respiratory dendritic cells in type 2 inflammatory responses, Supramolecular nanofiber vaccines, G6149753790, Immunomodulatory Biomaterials via Peptide and Protein Self-Assembly, Graduate Research Fellowship Program (GRFP), IRF4+ respiratory dendritic cells in type 2 inflammatory responses

OpenAlex ID: W3047746361

FWCI: 2.709

Cites: 40

Cited by: 47

Related to: 10