Work

Fibronectin matrix remodelling modulates the active nematic dynamics of cancer-associated fibroblasts

Year: 2026

Type: article

Source: Nature Materials

DOI: 10.1038/s41563-026-02615-5

Authors: Cécile Jacques, Louisiane Perrin, Joseph Ackermann, Samuel Bell, Olivier Zajac, Ambre Lapierre, Lucas Anger, Clément Hallopeau, Carlos Pérez-González, Lakshmi Balasubramaniam, Xavier Trepat, Benoît Ladoux, Ananyo Maitra, Raphael Voituriez, Danijela Matic Vignjevic

Institutions: Centre National de la Recherche Scientifique, Université Paris Sciences et Lettres, Biologie cellulaire et Cancer, Institut Curie, Université Paris Cité, École Normale Supérieure - PSL, Sorbonne Université, Laboratoire Jean Perrin, Laboratoire de Physique de l'Ecole Normale Supérieure, Institut Jacques Monod, University of Cambridge, The Gurdon Institute, Wellcome Trust, Institució Catalana de Recerca i Estudis Avançats, Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, Barcelona Institute of Science and Technology, Institute for Bioengineering of Catalonia, Universitat de Barcelona, Friedrich-Alexander-Universität Erlangen-Nürnberg, Max Planck Institute for the Science of Light, CY Cergy Paris Université, Laboratoire de Physique Théorique et Modélisation, Inserm, La Ligue Contre le Cancer

Language: English

Topic: Cellular Mechanics and Interactions

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Infrastructures en Biologie Santé et Agronomie, European Commission, Fondation pour la Recherche Médicale, H2020 European Research Council

Awards: G434337789, Understanding the mechanical control of cell extrusion in collective assemblies, supracellular contractility of myofibroblasts in gut homeostasis and cancer invasion, Engineering epithelial shape and mechanics: from synthetic morphogenesis to biohybrid devices

OpenAlex ID: W7163020977

FWCI: 15.12

Cites: 44

Cited by: 14

Related to: 10