Work

High Aspect Ratio Nanofibril Materials

Year: 2014

Type: article

Abstract: The present invention features linear and three-dimensional supramolecular materials self-assembled from block co-polymers comprising oligo(ethylene sulfide) (OES). The block copolymers assemble into fibrils, micelles, or matrices. The fibrillar materials are sensitive to oxidation, which leads to decreased OES block hydrophobicity and crystallinity, and increased water solubility of the polymer constituents. Molecular loading options, coupled with oxidative sensitivity, allow implantable or injectable fibrillar suspensions or cross-linked three-dimensional matrices to demonstrate significant biomedical potential, especially in the context of extracellular and intracellular molecular delivery and applications related to infection and disease.

Source: University of Chicago

DOI: 10.6082/044xp-bjd44

Authors: Hubbell, Jeffrey A., Brubaker, Carrie E., Velluto, Diana

Institution: University of Chicago

Language: English

Topic: Block Copolymer Self-Assembly

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7163040069

FWCI:

Cites:

Cited by:

Related to: 10