Work

Small molecules inhibitors of RAD51

Year: 2017

Type: article

Abstract: Embodiments concern methods and small molecule compositions for selectively inhibiting RAD51-mediated D-loop formation while preserving RAD51's ability to form nucleoprotein filaments. The selective RAD51 D-loop formation activity inhibitors DNA repair while minimizing replication-associated toxicity in normal tissue.

Source: University of Chicago

DOI: 10.6082/05kq4-pkt67

Authors: Connell, Philip P., Lv, Wei, Budke, Brian, Kozikowski, Alan

Institution: University of Chicago

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7163000220

FWCI:

Cites:

Cited by:

Related to: 10