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Figure S2 from Resistance to the KRASG12D Inhibitor MRTX1133 Is Associated with Increased Sensitivity to BET Inhibition

Year: 2026

Type: other

Abstract: Inhibition of histone acetylation enhances MRTX1133-induced apoptosis in drug-resistant PDAC cells but has no effect on parental cells

DOI: 10.1158/1535-7163.32530592

Authors: Daniel R. Principe, Jeffrey H. Becker, Anastasia E. Metropulos, Alejandra M. Marinelarena, Thao D. Pham, Alexandre F. Aissa, Hidayatullah G. Munshi

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7163066705

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