Postcardiotomy extracorporeal life support after isolated or valve-concomitant coronary artery bypass grafting: An observational multicenter study
Year: 2026
Type: article
Study design: Observational Study
Abstract: Objectives: Data on outcomes of patients undergoing isolated coronary artery bypass grafting (isolated CABG) versus CABG and concomitant left heart valve (LHV-CABG) surgery are conflicting, especially in extracorporeal life support (ECLS) settings. We compared characteristics, in-hospital outcomes, and overall survival between patients undergoing isolated-CABG and concomitant LHV-CABG requiring postcardiotomy ECLS from a large multicenter study. Methods: This retrospective, multicenter (34 centers), observational study included adults requiring postcardiotomy ECLS between 2000 and 2020. Clinical characteristics and outcomes were compared between patients who underwent isolated CABG with those who underwent LHV-CABG. Association between type of surgery and in-hospital survival was investigated through mixed-Cox proportional hazards models. Results: = .210) for isolated CABG and LHV-CABG groups, respectively. Conclusions: LHV-CABG surgery, compared with isolated CABG, was associated with higher in-hospital mortality in patients requiring ECLS, whereas no midterm postdischarge survival differences could be detected. Early identification of patients in need for ECLS following LHV-CABG may improve outcomes.
Source: JTCVS Open
Authors: Silvia Mariani, Sacha Matteucci, Bas C.T. van Bussel, Anne-Kristin Schaefer, Diyar Saeed, Matteo Pozzi, Luca Botta, Nikolaos Kalampokas, Agne Jankuviene, Karl Bounader, Xiaotong Hou, Jeroen J.H. Bunge, Hergen Buscher, Leonardo Salazar, Bart Meyns, Michael A. Mazzeffi, Sandro Sponga, Vitaly Sorokin, Claudio Russo, Michele Di Mauro, Pranya Sakiyalak, Antonio Fiore, Daniele Camboni, Giuseppe Maria Raffa, Rodrigo Diaz, I-wen Wang, Jae-Seung Jung, Jan Belohlavek, Vin Pellegrino, Giacomo Bianchi, Matteo Pettinari, Alessandro Barbone, José P. Garcia, Kiran Shekar, Glenn Whitman, Francesco Formica, Roberto Lorusso
Institutions: Maastricht University, Marche Polytechnic University, Azienda Ospedaliero-Universitaria delle Marche, Maastricht University Medical Centre, Care and Public Health Research Institute, Medical University of Vienna, Hôpital Louis Pradel, IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola, University of Bologna, Heinrich Heine University Düsseldorf, Vilnius University Hospital Santariskiu Klinikos, Hôpital Pontchaillou, Capital Medical University, Beijing Anzhen Hospital, Erasmus MC, St Vincent's Hospital Sydney, Fundación Cardiovascular de Colombia, KU Leuven, University of Maryland, Baltimore, University of Udine, National University Hospital, National University Health System, Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, University of Foggia, Siriraj Hospital, Mahidol University, Centre Hospitalier Universitaire Henri-Mondor, Hôpitaux Universitaires Henri-Mondor, University Hospital Regensburg, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, University of Palermo, Clínica Las Condes, Memorial Healthcare System, Korea University Anam Hospital, Charles University, The Alfred Hospital, Monash University, Fondazione Toscana Gabriele Monasterio, Ziekenhuis Oost-Limburg, IRCCS Humanitas Research Hospital, Indiana University Health, Methodist Hospital, Prince Charles Hospital, Johns Hopkins University, Johns Hopkins Medicine, University of Salento
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,431
OpenAlex ID: W7163417862