Report of high data rate macromolecular crystallography (HDRMX) meeting, 23 July 2025
Year: 2026
Type: article
Abstract: This paper is a report of the High Data Rate Macromolecular Crystallography workshop held on 23 July 2025 as part of the 2025 meeting of the American Crystallographic Association in Lombard, IL, USA, 18-23 July 2025. This report summarizes the discussions, questions, action items, and recommendations that arose from the meeting and includes links to the presentations. The sessions were moderated by Aaron S. Brewster and Graeme Winter. There was particularly lively discussion about the possible need for lossy compression as data rates increase, as multimodal experiments become more popular and as research budgets are squeezed.
Source: Structural Dynamics
DOI: 10.1063/4.0001196
Authors: Christine Beavers, Herbert J. Bernstein, Aaron S. Brewster, Max Burian, Nicholas Devenish, Jiaxin Dawn Duan, Daniel Eriksson, Diego Gämperle, Yang Ha, David R. Hall, James Holton, Peter Keller, Loes Kroon-Batenburg, David W. Mittan-Moreau, Yasukazu Nakaye, Daniel W. Paley, Ezra Peisach, Nicholas K. Sauter, Sofia Trampari, Clemens Vonrhein, David G. Waterman, Thomas A. White, Graeme Winter
Institutions: Rigaku (Japan), Brookhaven National Laboratory, Ronin Institute for Independent Scholarship 2.0, Lawrence Berkeley National Laboratory, DECTRIS (Switzerland), Diamond Light Source, Paul Scherrer Institute, Australian Synchrotron, University of California, San Francisco, SLAC National Accelerator Laboratory, Stanford Synchrotron Radiation Lightsource, University of California, Berkeley, Global Phasing (United Kingdom), Utrecht University, Worldwide Protein Data Bank, Rutherford Appleton Laboratory, Research Complex at Harwell, Deutsches Elektronen-Synchrotron DESY, Argonne National Laboratory, Advanced Photon Source
Language: English
Subfield: Structural Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,200
Funders: U.S. Department of Energy, UK Research and Innovation, Innosuisse - Schweizerische Agentur für Innovationsförderung, National Institutes of Health, College of Veterinary Medicine, Cornell University, University of California, San Francisco, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, Lawrence Berkeley National Laboratory, SLAC National Accelerator Laboratory, Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases
Awards: G1079818582, G1143651532, G1286236842, G1396440249, G1451874870, G2371548206, G2539837713, G262532246, G3083819904, G334911014, G382641700, G3884951186, G4235786860, G42916606, G4342761406, G4581610328, G4936682287, HARC Center: HIV Accessory and Regulatory Complexes, G5570207115, G5827283995, G7354628648, G8229677252, G8925327636, Bridging the Gap Between Prediction and Reality in Structural Biology, A Synchrotron Radiation Structural Biology Resource, ALS Efficiently Networking Advanced Beam Line Experiments (ALS-ENABLE), Cctbx.xfel: Serial crystallography computational methods aimed at biomolecular function, DIALS: supporting structural biology through open source diffraction processing software, G969889393
OpenAlex ID: W7163555956