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Filarial Worm Infestation of the Nasolacrimal Duct: A Rare Orbital Presentation

Year: 2026

Type: article

Abstract: ABSTRACT: Filarial infestation of the nasolacrimal duct is exceptionally rare and often misdiagnosed as benign lacrimal pathology. We present a 12-year-old boy with progressive medial canthal swelling initially suspected to be a dermoid cyst or inflammatory lesion. Magnetic resonance imaging revealed a well-defined enhancing lesion at the nasolacrimal duct with preseptal edema. Histopathology demonstrated a parasite with a thick eosinophilic cuticular wall and inflammatory infiltrate rich in eosinophils and foreign-body giant cells, consistent with filarial infestation, possibly Onchocerca species. Surgical excision followed by antifilarial therapy resulted in complete recovery without recurrence at 3-month follow-up. Heightened clinical awareness in endemic regions is essential to enable timely diagnosis and effective management.

Source: Annals of African Medicine

DOI: 10.4103/aam.aam_104_26

Authors: Tushar Kalekar, Jyothsna Yeluru

Institution: Dr. D. Y. Patil Medical College, Hospital and Research Centre

Language: French

Topic: Parasitic Diseases Research and Treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7163884630

FWCI:

Cites: 1

Cited by:

Related to: 10