Work

Process-intensified enzymatic decarboxylation using immobilized arylmalonate decarboxylase for sustainable asymmetric synthesis of α-arylpropionic acids

Year: 2026

Type: article

Abstract: Integrating alkaline saponification with enzymatic decarboxylation in a pH-stat rotating bed reactor suppresses racemic side reactions via anionic stabilization, ensuring high enantiopurity as a green alternative to hydrogenolysis.

Source: Green Chemistry

DOI: 10.1039/d6gc02400a

Authors: Jan Gerstenberger, Timm Werbilo, Marvin Haas, Simona Serban, Alessandra Basso, Pablo Domínguez de María, Selin Kara

Institutions: Leibniz University Hannover, Aarhus University

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Responsible consumption and production

Open Access status: hybrid

Funders: TU Graz, Internationale Beziehungen und Mobilitätsprogramme, Aarhus Universitets Forskningsfond, Gottfried Wilhelm Leibniz Universität Hannover, Niedersächsisches Ministerium für Wissenschaft und Kultur, Leibniz-Gemeinschaft

Awards: G638690918, G6513606930

OpenAlex ID: W7163892175

FWCI: 1.939

Cites: 70

Cited by: 1

Related to: