Work

Single-cell RNA-seq & single-cell ATAC-seq profiling of spleens from myelofibrosis patients

Year: 2025

Type: dataset

Abstract: This record provides Seurat objects containing single-cell RNA-seq and scATAC-seq profiling of spleens of patients with myelofibrosis, as well as non-cancerous spleens and normal bone marrow. Metadata includes: celltype.l1 (broad celltype) celltype.l2 (granular celltype, available for HSPCs and T/NK cells) sample tissue (NC = non-cancerous spleen, MF = myelofibrotic spleen, BM = normal bone marrow)

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.15603526

Authors: Austin, Rebecca, Kowalski, Madeline, Wang, Xiaoli, Lin, Ziyan, Nadorp, Bettina, Ward, Nicholas, Rovatti, Pier Edoardo, Lasry, Audrey, Sun, Zhengxi, Rojo-Tomillo, Julia, Gambi, Giovanni, Patel, Tejas, Zhou, Hua, MIA, MD BABU, Esteva, Eduardo, Dolgalev, Igor, Mezzano, Valeria, Ray, Suhita, Doulatov, Sergei, Gindin, Tatyana, Loghavi, Sanam, Psaila, Beth, Tsirigos, Aristotelis, Satija, Rahul, Aifantis, Iannis, Hoffman, Ronald

Institutions: NYU Langone Health, Icahn School of Medicine at Mount Sinai, New York University, The University of Texas MD Anderson Cancer Center, University of Oxford, Oxford University Hospitals NHS Trust

Language: English

Topic: Myeloproliferative Neoplasms: Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6912055696

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