Work

Improved oxygenation and hemocompatibility for microfluidic artificial lung via membrane microstreaming

Year: 2026

Type: article

Abstract: gas exchange into ovine blood is improved up to 2.6× compared to the non-actuated control, allowing blood pumped through the device to reach a 95% target for oxygen saturation with channel geometry and flow parameters, which would otherwise be unsuitable. Such a design allows for taller channel heights than those typically seen in microfluidic artificial lung devices while maintaining gas exchange efficiency, enabling the device to capitalize on the reduced coagulation associated with the taller, actuated channels, enabling easier fabrication by conventional machining, and allowing for larger throughput per channel branch.

Source: Lab on a Chip

DOI: 10.1039/d6lc00360e

Authors: Anthony Mercader, Sang-Ho Ye, William R. Wagner, Sung Kwon Cho

Institution: University of Pittsburgh

Language: English

Topic: Mechanical Circulatory Support Devices

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: hybrid

Funders: National Science Foundation, Division of Electrical, Communications and Cyber Systems

Awards: G7156273678, Collaborative Research: Integrated Swimming Microrobots for Intravascular Neuromodulation