Work

m6A-FORM: An m6A-focused Foundation Model for Decoding m6A Regulatory Function

Year: 2026

Type: preprint

Abstract: A sites linked to stronger methylation, reader binding, RBP occupancy and decay propensity.

Source: PubMed

DOI: 10.48550/arxiv.2606.12219

Authors: Zhang, Ting-He, Jo, Sumin, Gao, Shou-Jiang, Huang, Yufei

Institutions: University of Pittsburgh, UPMC Hillman Cancer Center, University of Pittsburgh Medical Center

Language: English

Topic: RNA modifications and cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: University of Pittsburgh, National Institutes of Health, Center for Research Computing, University of Pittsburgh, National Cancer Institute

Awards: High-Throughput Computing for Genomics and Bioinformatics Research, G642779400, G6966134840, Novel geometric deep learning models for tissue structure-aware spatial expression representations from spatially resolved single-cell transcriptomics data, G8887262216, Impact of microbiota on AIDS-Kaposi’s sarcoma development and therapy, Regulation of KSHV replication by N6-methyladenosine (m6A), METTL16 and S-adenosylmethionine cycle in KSHV infection, m6A-suite: an informatics pipeline and resource for elucidating roles of m6A epitranscriptome in cancer, Cancer Center Support Grant, Cell model for KSHV infection and genetic manipulation, Citrulline-urea cycle in KSHV cellular transformation

OpenAlex ID: W7164348851

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