Supplementary Figure S13 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity
Year: 2026
Type: supplementary-materials
Abstract: Immunoblot analysis of β-catenin in TWS119-treated or DMSO control T cells, NFAT activity assessed by eGFP fluorescence in non-activated or activated TPR cells treated with TWS119 or DMSO control, relative proteasome activity of T cells treated with 20SPA1 or DMSO control, relative protein aggregates accumulation in T cells treated with 20SPA1 or DMSO control, and relative expression of exhaustion markers in 20SPA1-treated or DMSO control T cells.
Authors: Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán, Leire Egia-Mendikute, Borja Jiménez-Lasheras, Alexandre Bosch, Adrián Barreira-Manrique, Iker Oyenarte, So Young Lee, Christoph Heuser-Loy, Jeremy G. Baldwin, Roland C. Schelker, Azucena Martín-Santos, Fabio Mastrogiovanni, Mikel Azkargorta, Felix Elortza, James D. Sutherland, Veronica Torrano, Ana M. Aransay, Lorena Pérez-Gutiérrez, Alena Gros, Santiago J. Carmona, Luca Gattinoni, June Ereño-Orbea, Endika Prieto-Fernández, Asis Palazon
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7164821882