Supplementary Figure S8 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity
Year: 2026
Type: supplementary-materials
Abstract: Genotyping of PGC-1α KO mice by PCR amplification of Cre recombinase and loxP flanking Ppargc1a sequences, numbers of CD4+, CD8+, and double positive T cells in the thymus and spleen of PGC-1α KO or WT mice, numbers of CD4+ and CD8+ T cells and B cells in the spleen of PGC-1α KO or WT mice, and production of proinflammatory cytokines and cytolytic molecules in T cells isolated from PGC-1α KO or WT mice.
Authors: Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán, Leire Egia-Mendikute, Borja Jiménez-Lasheras, Alexandre Bosch, Adrián Barreira-Manrique, Iker Oyenarte, So Young Lee, Christoph Heuser-Loy, Jeremy G. Baldwin, Roland C. Schelker, Azucena Martín-Santos, Fabio Mastrogiovanni, Mikel Azkargorta, Felix Elortza, James D. Sutherland, Veronica Torrano, Ana M. Aransay, Lorena Pérez-Gutiérrez, Alena Gros, Santiago J. Carmona, Luca Gattinoni, June Ereño-Orbea, Endika Prieto-Fernández, Asis Palazon
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7164856917