Work

Clinical outcomes of patients bilaterally implanted with the light adjustable lens: results of a phase IV clinical registry

Year: 2026

Type: article

Abstract: PURPOSE: To report the outcomes of the light adjustable lens (LAL) collected from a clinical registry. SETTING: Multiple private practices in the United States. DESIGN: Multicenter prospective observational study. METHODS: Patients who underwent bilateral LAL implantation and who had corrected distance visual acuity ≥20/20 -2 before lens adjustment were enrolled. Assessment was performed at one visit 1 to 3 months after final lock-in treatment. RESULTS: A total of 1101 participants (2202 eyes) were included. Of these, 586 eyes had prior corneal refractive surgery (CRS) and 1616 had no prior CRS (No CRS). 12.3% of participants were targeted for bilateral emmetropia, 9.3% for bilateral near, and 78.4% for blended vision. Of eyes targeted for emmetropia, 81.2% achieved a uncorrected distance visual acuity (UDVA) of ≥20/20 (82.2% of No CRS and 78.4% of CRS). A total of 94.3% of eyes targeted for emmetropia had a manifest spherical equivalent (MSE) of ≤0.5 diopter (D) (94.7% of No CRS, 92.8% of CRS). The mean prediction error in MSE was -0.048 ± 0.366 D in No CRS and -0.016 ± 0.441 D in CRS. A total of 89% of patients with blended vision and 93% of patients with bilateral emmetropic target had binocular UDVA of ≥20/20. In the CRS group, 87% with blended vision and 87% with binocular emmetropia achieved binocular UDVA of ≥20/20. Binocular uncorrected near visual acuity of ≥J1 was achieved with blended vision in 85% of patients in the No CRS group and 82% of patients in the CRS group. CONCLUSIONS: In this multicenter study, patients achieved a high degree of precision with the LAL regardless of prior CRS.

Source: Journal of Cataract & Refractive Surgery

DOI: 10.1097/j.jcrs.0000000000001994

Authors: Julie M. Schallhorn, Alekya Rajanala

Institution: University of California, San Francisco

Language: English

Topic: Intraocular Surgery and Lenses

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,000