Work

Virion display reveals MD-1 as an endogenous agonist for the orphan receptor GPRC5B

Year: 2026

Type: article

Source: Science Signaling

DOI: 10.1126/scisignal.adr8554

Authors: Eric Johansen, Guan-Da Syu, Zijian Wan, Dylan C. Sarver, Meng Ding, Xinzhong Dong, Shaopeng Wang, G. William Wong, Heng Zhu

Institutions: Johns Hopkins University, Johns Hopkins Medicine, National Cheng Kung University, Arizona State University, Howard Hughes Medical Institute

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Science and Technology Council, National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke

Awards: G1945957118, Regulation of Retinal Development by RNA molecules, G6647368250, The Chemistry-Biology Interface Program at Johns Hopkins University, G9000048810, G9000206749, CTRP and Metabolic Control, Multidisciplinary approach to study of patients with Severe Alcoholic Hepatitis Undergoing Liver Transplantation, Identification and characterization of mCpH binding proteins in neurons, Clinical Resource for Alcoholic Hepatitis Inestigation, Multidisciplinary Training Program in Lung Disease

OpenAlex ID: W7164920788

FWCI:

Cites: 28

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