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Supplementary Figure 10 from A Covalent Allosteric Molecular Glue Suppresses NRF2-Dependent Cancer Growth

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Year: 2026
Type: supplementary-materials
Abstract: Shows the anti-proliferative activity of VVD-065, observed across various cell lines and potentiated in 3D culture, is fundamentally linked to the presence of KEAP1 Cys151
DOI: 10.1158/2159-8290.32702009
Authors: Nilotpal Roy, Tine Wyseure, I-Chung Lo, Justine Lu, Christie L. Eissler, Steffen M. Bernard, Ilah Bok, Aaron N. Snead, Albert Parker, U-Ging Lo, Jason C. Green, Jordon Inloes, Sarah R. Jacinto, Brent Kuenzi, Marie Pariollaud, Kathleen Negri, Khoi Le, Benjamin D. Horning, Noah Ibrahim, Stephanie Grabow, Harit Panda, Dhaval P. Bhatt, Emily M. Wilkerson, Soma Saeidi, Paul Zolkind, Zoe Rush, Heather N. Williams, Eric Walton, Martha K. Pastuszka, John J. Sigler, Eileen Tran, Kenneth Hee, Joseph McLaughlin, Géza Ambrus-Aikelin, Jonathan Pollock, Robert T. Abraham, Todd M. Kinsella, Gabriel M. Simon, Michael B. Major, David S. Weinstein, Matthew P. Patricelli
Language: English

Topic: Genomics, phytochemicals, and oxidative stress
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: gold
OpenAlex ID: W7164988804
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Related to: 10
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