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Therapeutic potential of metabotropic glutamate receptor 7 modulation in correcting cognitive deficits of schizophrenia

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Year: 2026
Type: article
Abstract: is proposed to be a viable therapeutic target to treat cognitive deficits driven by glutamatergic dysfunction in disorders including schizophrenia.
Source: Schizophrenia Research
DOI: 10.1016/j.schres.2026.06.012
Authors: Niki M. Harris, Kimberly M. Holter, Colleen M. Niswender
Institutions: Vanderbilt University, Vanderbilt University Medical Center
Language: English

Topic: Schizophrenia research and treatment
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: hybrid
Estimated APC paid: $3,910

Funders: Vanderbilt University, National Institutes of Health, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke
Awards: Development of mGlu7 receptor allosteric modulators for neurological and psychiatric disorders, G2777262153, G488929812, G6175029438, G87902941, Impact of Metabotropic Glutamate Receptor Heteromerization on Signaling and Pharmacology, Regulation of metabotropic glutamate receptor activity by protein/protein interactions, Metabotropic glutamate receptor 7 as a potential genetic modifier of cognitive deficits in neurofibromatosis, G928359606, G990641700
OpenAlex ID: W7164994818
FWCI:
Cites: 197
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