Work

Supplementary Figure 8 from Intermittent MEK Inhibition with GITR Costimulation Rescues T-cell Function for Increased Efficacy with CTLA-4 Blockade in Solid Tumor Models

Year: 2026

Type: supplementary-materials

Abstract: Supplementary Figure 8. Intermittent CKI27 treatment and GITR co-stimulation relieves expression of activation markers. Representative dot plot data for FACS analysis of activation markers expressed by CD8+ T cells.

DOI: 10.1158/2326-6066.32702667

Authors: Lauren Dong, Hyejin Choi, Sadna Budhu, Isabell Schulze, Svena Verma, Levi M. Mangarin, Valeria Estrada Nevarro, Nezar Mehanna, Jonathan F. Khan, Divya Venkatesh, Daniel Thach, Neal Rosen, Jedd D. Wolchok, Taha Merghoub

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7165010010

Cites:

Cited by:

Related to: