Work

Interactions between gonadal hormones and neurovascular responses to the cold pressor test in young healthy females

Year: 2026

Type: article

Abstract: In this pooled cohort of young, healthy females assessed during the early follicular phase of the menstrual cycle or placebo phase of the oral contraceptive pill cycle, correlation analyses indicated that those with the highest free androgen index demonstrated 1) the greatest increases in sympathetic activity and 2) decreases in peripheral vascular conductance during the cold pressor test. These data suggest that bioavailable testosterone may be linked to sympathetic neurovascular responses to acute stress.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00438.2026

Authors: Yasmine Coovadia, Emily K. Van Berkel, Laila A. Chaudhry, Brittany K. Schwende, Divine Malenda, Charlotte W. Usselman

Institutions: McGill University, Research Institute of the McGill University Health Centre

Language: English

Topic: Hormonal and reproductive studies

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Natural Sciences and Engineering Research Council of Canada