Work

Artificial Avidity Optimization of T-cell Receptors by Integrating Deep Learning Model and Mammalian Cell Surface Display

Year: 2026

Type: article

Source: Phenomics

DOI: 10.1007/s43657-025-00295-w

Authors: Mengmeng Wei, Shengzuo Bai, Wenfan Chen, Jingcheng Wu, Yi Pan, Wenyi Zhao, Wenhui Qian, Ji Cao, Gang Pan, Xueli Bai, Ruhong Zhou, Wenbin Zhao, Shuqing Chen, Zhan Zhou

Institutions: Zhejiang University, Westlake University, Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine, First Affiliated Hospital Zhejiang University

Language: English

Topic: vaccines and immunoinformatics approaches

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Natural Science Foundation of China, Natural Science Foundation of Zhejiang Province

Awards: 冠状病毒演化规律、互作机制与防治关键技术研究, G3463876631, G4471133494, 基于多模态深度学习的肿瘤新抗原疫苗设计研究, 基于多组学数据整合和异构图表示学习的癌症个性化驱动基因识别研究

OpenAlex ID: W7165014571

FWCI:

Cites: 102

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Related to: 10