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Supplementary Figure S14 from Contrasting Features of Papillary and Chromophobe Renal Cell Carcinoma Revealed by Whole-Genome Sequencing

Year: 2026

Type: supplementary-materials

Abstract: Supplementary Figure S14. Mutation and copy number timing. The relative ordering of driver mutations and arm level alterations. Copy number alterations refer to both gains and losses that encompass at least 50% of the chromosome arm. The odds ratio (OR) and 95% confidence intervals refer to the likelihood that a driver event is early (Log(OR) < 0) or late (Log(OR) > 0) and are calculated empirically from simulation (Supplementary Methods S1).A, ChRCC (n = 61). B, pRCC (n = 103).

DOI: 10.1158/1541-7786.32712838

Authors: Richard Culliford, Charlie Mills, Daniel Chubb, Ben Kinnersley, Amit Sud, Alex J. Cornish, Lisa Browning, Samuel E.D. Lawrence, Robert Bentham, Anna Frangou, Andreas J. Gruber, Kevin Litchfield, David C. Wedge, James Larkin, Samra Turajlic, Richard S. Houlston

Language: English

Topic: Renal cell carcinoma treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7165043316

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