Work

A Cathepsin B -Cleavable Self-Immolative Linker for the Delivery of Hydroxyl-Containing Payloads in Antibody–Drug Conjugates

Year: 2026

Type: article

Source: Bioconjugate Chemistry

DOI: 10.1021/acs.bioconjchem.6c00121

Authors: Xiaomei Li, Xuzhuo Li, Xing Jiang, Yingxin Lu, Lizhe Bai, Yue Guo, Yalong Li, Wei Lu, Mengyuan Ding, Shulei Zhu

Institutions: East China Normal University, Chinese Academy of Sciences, Shanghai Institute of Materia Medica, State Key Laboratory of Drug Research

Language: English

Topic: Monoclonal and Polyclonal Antibodies Research

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Shanghai Rising-Star Program, National Science and Technology Major Project

Awards: G1633022480, G3448826046, G4183591777

OpenAlex ID: W7165043736

FWCI: 4.52

Cites: 24

Cited by: 1

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