Work

Supplementary Table S15 from Contrasting Features of Papillary and Chromophobe Renal Cell Carcinoma Revealed by Whole-Genome Sequencing

Year: 2026

Type: supplementary-materials

Abstract: Supplementary Table S15: Summary of mutations explained by COSMIC signatures. Signatures which are suspected to be signature artifacts are not included. Percentage of mutation burden refers to the percentage of either the total single base substitutions (SBS) or indels (ID) explained by a COSMIC signature for each patient. ChRCC, chromophobe renal cell carcinoma; ID1, slippage during DNA replication of the replicated DNA strand; ID2, slippage during DNA replication of the replicated DNA strand; ID12, unknown aetiology; pRCC, papillary renal cell carcinoma SBS1, spontaneous deamination of 5-methylcytosine (clock-like signature); SBS5, unknown (clock-like signature); SBS26, defective DNA mismatch repair; SBS44, defective DNA mismatch repair.

DOI: 10.1158/1541-7786.32712775

Authors: Richard Culliford, Charlie Mills, Daniel Chubb, Ben Kinnersley, Amit Sud, Alex J. Cornish, Lisa Browning, Samuel E.D. Lawrence, Robert Bentham, Anna Frangou, Andreas J. Gruber, Kevin Litchfield, David C. Wedge, James Larkin, Samra Turajlic, Richard S. Houlston

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7165048404

Cites:

Cited by:

Related to: 10