Supplementary Figure S6 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
Year: 2026
Type: supplementary-materials
Abstract: Supplementary Figure S6 shows densitometry analysis for pERK and pAKT in a western blot experiment in KRASG12D and KRASG12D/A59G cells treated with BBO-11818 or DMSO.
Authors: Carlos Stahlhut, Anna E. Maciag, Kyle A. Sullivan, Kanchan Singh, Nadege Gitego, Zuhui Zhang, Albert H. Chan, Alok K. Sharma, Patrick A. Alexander, Jin Shu, Yue Yang, Megan Rigby, Roger Ma, Saman Setoodeh, Brian P. Smith, Jun Pei, Dana Rabara, Erik K. Larsen, David M. Turner, Cathy Zhang, Cindy Feng, Siyu Feng, James P. Stice, Rui Xu, Ken Lin, Andrew G. Stephen, Felice C. Lightstone, Chunmei Ji, Keshi Wang, Dhirendra K. Simanshu, Dwight V. Nissley, Eli Wallace, Bin Wang, Kerstin W. Sinkevicius, Frank McCormick, Pedro J. Beltran
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W7165052535