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Supplementary Figure 6 from A Covalent Allosteric Molecular Glue Suppresses NRF2-Dependent Cancer Growth

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Year: 2026
Type: supplementary-materials
Abstract: Shows further evaluation of VVD-065, including assessment of the acetamide analog's lack of activity, determination of VVD-065 reaction kinetics, and additional structural analysis of the compound
DOI: 10.1158/2159-8290.32701967
Authors: Nilotpal Roy, Tine Wyseure, I-Chung Lo, Justine Lu, Christie L. Eissler, Steffen M. Bernard, Ilah Bok, Aaron N. Snead, Albert Parker, U-Ging Lo, Jason C. Green, Jordon Inloes, Sarah R. Jacinto, Brent Kuenzi, Marie Pariollaud, Kathleen Negri, Khoi Le, Benjamin D. Horning, Noah Ibrahim, Stephanie Grabow, Harit Panda, Dhaval P. Bhatt, Emily M. Wilkerson, Soma Saeidi, Paul Zolkind, Zoe Rush, Heather N. Williams, Eric Walton, Martha K. Pastuszka, John J. Sigler, Eileen Tran, Kenneth Hee, Joseph McLaughlin, Géza Ambrus-Aikelin, Jonathan Pollock, Robert T. Abraham, Todd M. Kinsella, Gabriel M. Simon, Michael B. Major, David S. Weinstein, Matthew P. Patricelli
Language: English

Topic: Genomics, phytochemicals, and oxidative stress
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: gold
OpenAlex ID: W7165062572
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Related to: 10
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