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Liver Background Uptake of Prostate-specific Membrane Antigen–targeted PET Radiotracers: A Systematic Review and Meta-Analysis

Year: 2026

Type: review

Abstract: Higher liver background uptake was observed on prostate-specific membrane antigen (PSMA)–targeted PET imaging with fluorine 18 ( 18 F)-flotufolastat and 18 F-PSMA-1007 compared with 18 F-piflufolastat and gallium 68 ( 68 Ga)-PSMA-11, which may influence patient eligibility for PSMA-targeted therapy.

Source: Radiology Imaging Cancer

DOI: 10.1148/rycan.250732

Authors: Gary A. Ulaner, Ashwin S. Parihar, Jeremie Calais, Siobhan Sutcliffe, Jan W. Schoones

Institutions: University of Southern California, Washington University in St. Louis, University of California, Los Angeles, Leiden University Medical Center

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7165143172

FWCI:

Cites: 32

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