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Xylazine’s κ relatively potent opioid agonist activity is not shared with other US Food and Drug Administration-approved α2-adrenergic agonists

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Year: 2026
Type: article
Source: Journal of Pharmacology and Experimental Therapeutics
DOI: 10.1016/j.jpet.2026.104969
Authors: Xi-Ping Huang, Brian E. Krumm, Madigan L. Bedard, Zoe A. McElligott, Bryan L. Roth
Institutions: University of North Carolina at Chapel Hill, National Institute of Mental Health
Language: English

Topic: Receptor Mechanisms and Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Institutes of Health, University of North Carolina at Chapel Hill, National Institute of Mental Health
Awards: An informatics approach to examine genetic and environmental regulation of the PI3K-AKT-mTOR pathway in autism spectrum disorder, G8691474425
OpenAlex ID: W7165365757
FWCI:
Cites: 32
Cited by:
Related to: 10
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