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Figure 1 from Nanoparticulate Immunoactive Complex for Local Chemoimmunotherapy: From Murine Models to Pilot Canine Study

Year: 2026

Type: other

Abstract: Locally injected IMAX is retained at the injection site with minimal systemic absorption. PTX levels (μg/g) in skin (or tumor) and (ng/mL) in plasma at 6, 24, and 48 hours after subcutaneous or intratumoral injection of IMAX (containing 1 mg 2E′) in healthy and CT26 tumor-bearing BALB/c mice (7–8 weeks). n = 4 mice per time point. Data are the mean ± SD. P value was calculated by Sidak multiple comparisons test, following two-way ANOVA.

DOI: 10.1158/2767-9764.32759123

Authors: Yanying He, Jiaqi Zhao, Jung Suk Kim, Meaghan M. Broman, Simone de Brot, Fanfei Meng, Deepika Dhawan, Sagar M. Utturkar, Marejka H. Shaevitz, Lindsey M. Fourez, Deborah W. Knapp, Yoon Yeo

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7165534697

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