Work

Tradeoffs between targeted and expanded testing strategies for influenza A(H5N1)

Year: 2026
Type: editorial
Abstract: , G. P. Higerd-Rusli, A. Karan, S. A. Hoffman, I. E. A. Morante, et al. (ASM Case Rep 2:e00165-25, 2025, https://doi.org/10.1128/asmcr.00165-25) describe one confirmed and one probable case of influenza A(H5N1) detected through universal subtyping of influenza A-positive specimens, including cases without known animal exposure. These findings highlight the limitations of exposure-based testing strategies and raise important questions about early detection of emerging pathogens. Drawing on lessons from prior pandemics, this commentary examines the tradeoffs between targeted and expanded surveillance and emphasizes the need for adaptive, flexible approaches to laboratory preparedness.
Institution: Columbia University
Language: English
Subfield: Epidemiology
Field: Medicine
Open Access status: hybrid
OpenAlex ID: W7165759628
Cites: 18
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