Work

Concurrent Inhibition of ICMT and RAF/MEK Suppresses RAC1P29S-Driven MAPK Pathway Inhibitor Resistance in BRAFV600E Melanoma by Regulating TAZ Activity

Year: 2026

Type: article

Source: Molecular Cancer Therapeutics

DOI: 10.1158/1535-7163.mct-25-0919

Authors: Xiaoyang Gu, Patrick J. Casey, Mei Wang

Institutions: Duke-NUS Medical School, Duke University, Duke Medical Center, National University of Singapore

Language: English

Topic: Melanoma and MAPK Pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: National Medical Research Council

Award: G5046145031

OpenAlex ID: W7165763537

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