Year: 2026
Type: article
Abstract: Cancer metabolism has re-emerged as a central hallmark of tumor biology, reflecting the dynamic interplay between oncogenic signaling, cellular plasticity, and the tumor microenvironment. Building on foundational discoveries of altered glucose utilization and bioenergetics, recent advances have expanded this framework to encompass a diverse network of metabolic pathways, including lipid remodeling, nucleotide synthesis, redox homeostasis, and mitochondrial dynamics. These processes not only sustain tumor growth but also actively shape cancer cell fate, therapeutic response, and interactions with immune and stromal compartments.
Source: Oncogenesis
Author: Shensi Shen
Institutions: Sichuan University, West China Hospital of Sichuan University
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $4,290
OpenAlex ID: W7165775398