Work

Design, synthesis, and antibacterial activity study of pyrroloquinazoline diamine derivatives

Year: 2026

Type: article

Abstract: as a promising lead for developing novel, broad-spectrum DHFR inhibitors with a low resistance risk.

Source: Journal of Enzyme Inhibition and Medicinal Chemistry

DOI: 10.1080/14756366.2026.2690351

Authors: Muchun Cheng, YaJing Tian, JieYa Shang, Weiqing He, Ying Zheng, Can Yan, Xinyu Chen, Jiawei Li, YuanYing Jiang, Qiang Fu, Xianqing Deng, Xunli Xiao, Mingxia Song

Institutions: Jinggangshan University, Tongji University

Language: English

Topic: Quinazolinone synthesis and applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,306

Funders: National Natural Science Foundation of China, Natural Science Foundation of Jiangxi Province

Award: G8380701088

OpenAlex ID: W7165795937

FWCI:

Cites: 26

Cited by:

Related to: