Caregivers’ Perspectives on Cancer-Related Cognitive Impairment in Older Adults With Acute Myeloid Leukemia Receiving Chemotherapy
Year: 2026
Type: article
Abstract: PURPOSE: To explore caregivers' perspectives on cancer-related cognitive impairment (CRCI) experiences in older adults with acute myeloid leukemia receiving chemotherapy. PARTICIPANTS & SETTING: Eight caregivers, including adult children and spouses, of older adults with acute myeloid leukemia receiving chemotherapy from the control arm of a clinical trial were interviewed. METHODOLOGIC APPROACH: Semistructured interviews were conducted at the second, fourth, and seventh cycles of chemotherapy. All interviews were audio recorded and transcribed verbatim. Two researchers independently analyzed 16 transcripts using thematic analysis. FINDINGS: Four themes were identified: (a) CRCI experiences, (b) impact of CRCI, (c) CRCI coping strategies, and (d) perceived CRCI-related factors. Caregivers observed changes in memory, concentration, and information processing in their loved ones and developed various strategies to better support or cope with CRCI. In addition, CRCI influenced caregivers' emotions, lives, and relationships with their loved ones. IMPLICATIONS FOR NURSING: Caregivers of older adults with acute myeloid leukemia play a vital role in CRCI symptom monitoring. The impact of CRCI on caregivers highlights the importance of supporting caregivers, and the identified coping strategies can provide guidance for future intervention development.
Source: Oncology nursing forum
Institution: University of North Carolina at Chapel Hill
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: Gates Ventures, Transcan, Bill and Melinda Gates Foundation, Conquer Cancer Foundation, Tobacco-Related Disease Research Program, Natural Science Foundation of Shanghai, Foundation for Barnes-Jewish Hospital, Cutaneous Lymphoma Foundation, Japan Agency for Medical Research and Development, Regeneron Pharmaceuticals, Wellcome Trust, Chartered Society of Physiotherapy Charitable Trust, UK Research and Innovation, Flu Lab, National Institute for Health and Care Research, Hunter Medical Research Institute, Indian Council of Medical Research, Deutsche Forschungsgemeinschaft, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, University of Melbourne, National Natural Science Foundation of China, Ministry of Education of the People's Republic of China, China Postdoctoral Science Foundation, Else Kröner-Fresenius-Stiftung, Natural Science Foundation of Fujian Province, Natural Science Foundation of Guangdong Province, Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg, National Research Foundation of Korea, Vetenskapsrådet, Schweizerische Herzstiftung, Chinese Academy of Medical Sciences, Schweizerische Akademie der Medizinischen Wissenschaften, Novo Nordisk Fonden, Tri-Service General Hospital, Tianjin Municipal Bureau of Public Health, Julius Clinical, Alzheimer’s Society, VLIRUOS, Sickkids Research Institute, National Institutes of Health, HORIZON EUROPE Framework Programme, Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council of Canada, Innovate UK, Sanming Project of Medicine in Shenzhen, National Key Research and Development Program of China, NIHR Cambridge Biomedical Research Centre, Basic and Applied Basic Research Foundation of Guangdong Province, National Institute on Alcohol Abuse and Alcoholism, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Institute on Drug Abuse, National Institute of Allergy and Infectious Diseases, Fogarty International Center, National Institute of Diabetes and Digestive and Kidney Diseases, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Science and Technology Department of Zhejiang Province
OpenAlex ID: W7165808005
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