Work

GPX4-Targeting Phenolato Zr IV Complexes Induce Ferroptosis and Lysosome-Dependent Cell Death for Immunotherapy of Chemoresistant Cancer

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c01164

Authors: Tiankun Zhao, Jialiu Zhao, Jing Ma, Dongyu Mei, Yinan Ding, Qi-Pin Qin, Isabel Correia, Hong Liang

Institutions: Lanzhou University of Technology, Yulin Normal University, Guangxi Normal University, State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, University of Lisbon, Instituto Superior Técnico, Centro de Química Estrutural

Language: English

Topic: Ferroptosis and cancer prognosis

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Natural Science Foundation of Guangxi Zhuang Autonomous Region, National Natural Science Foundation of China, Natural Science Foundation of Gansu Province, Science and Technology Department of Gansu Province, Bagui Scholars Program of Guangxi Zhuang Autonomous Region, Fundação para a Ciência e a Tecnologia

Awards: G1978770307, Instituto de Ciências Moleculares, G338512240, G3557452669, G3614404109, G4252661487, G4465404848, G5324544498, G7907345377

OpenAlex ID: W7165869202

FWCI: 4.618

Cites: 58

Cited by: 1

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